Imipramine
In stock
75mg · 50mg · 25mg
from A$52.02
In brief
Imipramine, a tricyclic antidepressant sold in Australia as Tofranil, is listed for major depression and for night-time bed-wetting in children from 5 years once physical causes are excluded.
Imipramine (Tofranil): two listed uses
Major depression is the first use given for Tofranil by healthdirect. The second is nocturnal enuresis, or bed-wetting at night, in children aged 5 and over when an organic cause has been ruled out. Imipramine hydrochloride is a tricyclic antidepressant.
This listing shows imipramine 25 mg, 50 mg and 75 mg. It does not name the manufacturer of the tablets supplied, so check the label on the pack you receive and confirm with your prescriber or pharmacist that it matches your prescription.
25 mg: pack prices compared
Compare packs of the same strength. These examples are for 25 mg and are calculated from the listed prices at the shop’s Australian-dollar rate on 8 October 2026, before delivery or other checkout charges.
| Strength | Pack size | Pack price | Price per tablet |
|---|---|---|---|
| 25 mg | 60 | A$71.81 | A$1.20 |
| 25 mg | 120 | A$119.22 | A$0.99 |
| 25 mg | 180 | A$152.26 | A$0.85 |
Per tablet, the 120 pack saves roughly 17.0% and the 180 pack roughly 29.3% compared with the 60 pack.
A lower price per tablet means a larger upfront payment. Choose only the quantity and strength appropriate to your prescription, and check the expiry date. Prices can change, so confirm the current pack price before ordering.
Tofranil in Australia
Amdipharm Mercury (Australia) supplies Tofranil as sugar-coated 10 mg and 25 mg tablets. healthdirect lists it as Schedule 4 (Prescription Only) and PBS-subsidised. The 50 mg and 75 mg options on this page are not Tofranil strengths in that listing.
When it should not be taken
The Tofranil consumer medicine information rules it out for people allergic to imipramine or other tricyclics, for anyone recovering from a recent heart attack, and alongside MAO inhibitors; after stopping an MAO inhibitor, two weeks must pass first.
Precautions in the Tofranil leaflet
- Suicidal thoughts are a risk, particularly for young people; contact the doctor at once if they occur.
- Do not stop without first asking the doctor; improvement may take 4 to 6 weeks to be felt.
- Glaucoma, urinary problems, seizures and heart disease call for caution.
- Avoid alcohol, and do not drive until you know how you react.
- healthdirect notes particular risks over 65 and advises medical or pharmacist advice in pregnancy.
Side effects and interactions
Weight gain, sexual dysfunction, blurred vision, dry mouth, constipation, drowsiness and dizziness are listed as common. Uncontrolled movements, severe confusion, irregular heartbeat and allergic reactions are serious. Interacting products named in the leaflet include nicotine products, some cold medicines, warfarin, anticonvulsants, SSRIs, blood pressure medicines and MAO inhibitors.
Storage
healthdirect gives below 30 °C and protection from moisture for Tofranil. Follow the storage directions on the pack you receive.
Frequently asked questions
How soon does imipramine start to help with depression?
The Tofranil leaflet says noticeable improvement can take up to 4 to 6 weeks.
From what age is Tofranil listed for bed-wetting?
From 5 years, once physical causes have been excluded.
Delivery across Australia
Standard delivery: 14–22 days. Express tracked delivery: 7–14 days, with the tracking number sent by email. These are estimated delivery times, not guaranteed arrival dates.
Australian cities and delivery information
The Australian delivery options above apply to the destinations below. A city listing does not indicate a physical pharmacy branch or local stock.
| City | State or territory |
|---|---|
| Sydney | New South Wales |
| Melbourne | Victoria |
| Brisbane | Queensland |
| Perth | Western Australia |
| Adelaide | South Australia |
| Hobart | Tasmania |
| Gold Coast | Queensland |
| Canberra | Australian Capital Territory |
| Cairns | Queensland |
| Central Coast | New South Wales |
| Townsville | Queensland |
| Darwin | Northern Territory |
| Newcastle | New South Wales |
| Geelong | Victoria |
| Gladstone | Queensland |
| Port Macquarie | New South Wales |
| Bathurst | New South Wales |
| Forbes | New South Wales |
| Geraldton | Western Australia |
| Goulburn | New South Wales |
